Overview

Novare Pharmaceuticals is a biotechnology company focused on developing therapeutic products that help the body replenish and rebuild itself using its own tissue through the modulation of the Receptor for Hyaluronan Mediated Motility, or RHAMM.

RHAMM is a protein that is normally localized inside the cell but is released by certain stimuli. It plays a role in the regulation of spontaneous cell movement and stem cell differentiation. The modulation of RHAMM can provide a safe and efficacious means to selectively promote subcutaneous fat generation (adipogenesis), moderate destructive inflammation, and reduce scarring (fibrosis) by stimulating normal cell differentiation and controlling the body’s own natural regenerative processes.

Novare is developing a dermal filler for aesthetic applications that works via the modulation of RHAMM. This research is being led by Dr. Eva Turley, an oncology scientist at the London Health Sciences Centre (LHSC) in London, Ontario, in collaboration with MJ Bissell, a world-renowned cell biologist at Lawrence Berkeley National Laboratories in Berkeley, California.

Turley and her colleagues have also uncovered the potential for additional applications of RHAMM modulation that may help solve some of today’s biggest medical challenges, including arthritis, fibrotic diseases such as Bronchopulmonary Dysplasia (BPD) in premature infants and Idiopathic Pulmonary Fibrosis (IPF), and the reduction and possible elimination of keloid scars.

This breakthrough in tissue engineering may also provide an opportunity to regenerate and reconstruct women’s breasts after a mastectomy through the localized stimulation of the body’s own adipocyte (fat) stem cells.

More information about Novare and its research can be found on the company’s website:

www.novarepharma.com




Dr. Mina Bissell - Ted Talks

Announcements

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07-Oct-2014

Allied Minds Announces the Launch of Novare Pharmaceuticals

Allied Minds Announces the Launch of Novare Pharmaceuticals, a Biotech Company Focused on Developing Therapeutics that Modulate RHAMM Novare is an expans..

05-May-2014

ProGDerm Names J. Michael Delmage, Ph.D. as Chief Executive Officer

Boston (May 5, 2014) – ProGDerm, a biotechnology company that’s developing a natural approach to skin rejuvenation, today named J. Michael Delmage, Ph.D. as th..

27-Feb-2012

ProGDerm Enters Strategic Partnership to Develop New Active Ingredients in Skin Care

Boston, Massachusetts – ProGDerm, Inc., an Allied Minds company, developing a natural approach to skin rejuvenation, announced today that it entered into a strategic par..

07-Oct-2009

Luminous Skin - ProGDerm Featured in Allure Magazine

Full article can be found at: Allure Column October 2009 (/_literature_39944/Allure_October_2009) by Kristin Sainani ..

04-Nov-2008

New Skin Rejuvenation Discovery Receives Commercial Backing

Boston, Massachusetts - Allied Minds funds research to reduce wrinkles by developing a natural replacement for artificial dermal fillers. Allied Minds, a seed investment f..

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